Rylee's Run 5k is an annual charity run organized by Memphis Soccer in Memphis, Tennessee. The run commemorates the life of Rylee Rae Vinson, who was born August 16, 2007, at thirty-two weeks and passed away eight days later due to complications of premature birth. Rylee’s parents, Jason and Jessica Vinson, established the RIBS soccer tournament and Rylee's Run 5k to help raise money for the charities that have meant to much to them over the last several years - specifically, LeBonheur Children's Hospital's Neuroscience Institute and Neonatal Intensive Care Unit (NICU).

Participants will expect to run on a flat, circular route along the road and pathways of the Mike Rose Soccer Complex.